Bioactivity | [99m Tc]Tc-6-1, a 99mTc-labeled FAPI-46 derivative, is a specific fibroblast activation protein (FAP)-targeted radiotracer. [99m Tc]Tc-6-1 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging[1]. |
Invitro | [99mTc]Tc-6-1 表现出高靶标与非靶标比率(肿瘤/血液:6.06;肿瘤/肌肉:10.26)和良好的肿瘤摄取(16.15% ID/g),对 FAP 也具有高的亲和力。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> [99mTc]Tc-6–1 相关抗体: |
Formula | C43H46F2N11NaO7S |
Molar Mass | 921.95 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Qing Ruan, et al. Synthesis and Preclinical Evaluation of Novel 99mTc-Labeled FAPI-46 Derivatives with Significant Tumor Uptake and Improved Tumor-to-Nontarget Ratios. J Med Chem. 2024 Feb 22;67(4):3190-3202. |