PeptideDB

[99mTc]Tc-6–1

CAS: F: C43H46F2N11NaO7S W: 921.95

Tc-6-1, a 99mTc-labeled FAPI-46 derivative, is a specific fibroblast activation protein (FAP)-targeted radiotracer. Tc-6
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Bioactivity [99m Tc]Tc-6-1, a 99mTc-labeled FAPI-46 derivative, is a specific fibroblast activation protein (FAP)-targeted radiotracer. [99m Tc]Tc-6-1 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging[1].
Invitro [99mTc]Tc-6-1 表现出高靶标与非靶标比率(肿瘤/血液:6.06;肿瘤/肌肉:10.26)和良好的肿瘤摄取(16.15% ID/g),对 FAP 也具有高的亲和力。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> [99mTc]Tc-6–1 相关抗体:
Formula C43H46F2N11NaO7S
Molar Mass 921.95
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Qing Ruan, et al. Synthesis and Preclinical Evaluation of Novel 99mTc-Labeled FAPI-46 Derivatives with Significant Tumor Uptake and Improved Tumor-to-Nontarget Ratios. J Med Chem. 2024 Feb 22;67(4):3190-3202.